Ausschreibung UPGRADE 2023

10^th DKTK Joint Funding Call "UPGRADE 2023" is completed!

With the DKTK Joint Funding Program line UPGRADE, DKTK supports collaborative research modules that complement existing IITs/clinical studies with limited “add‐on” funding for up to 3 years. The underlying IIT/clinical study may or may not be DKTK funded.

A total of 19 proposals have been submitted during this call. The following three research modules were selected for funding:
 

• Precision monitoring and targeting of T-ALL (IDENTI-T): Decoding cellular identities of T-ALL for therapeutic monitoring and targeting by single-cell multi-omics and data-informed cytometry.
  
  Overall coordinators: Prof. Ulrich Keller, PD Dr. Stefan Schwartz, Berlin
  Participating DKTK sites: Berlin, Frankfurt/Mainz, Heidelberg
  
   
• Tumor heterogeneity impacts immunotherapy (TRICKY): Tumor heterogeneity impacts patient outcomes upon immune checkpoint inhibition in melanoma.
  
  Overall coordinator: Prof. Selma Ugurel, Essen/Düsseldorf
  Participating DKTK sites: Dresden, Essen/Düsseldorf, Heidelberg
  
   
• Translational program of IT-PD1/NOA-26 study (TRUST): Translational research program using longitudinal biosamples from enrolled patients during intrathecal immunotherapy within the multicenter investigator-inititated IT-PD1/NOA-26 clinical study.

Overall coordinator: Prof. Ghazaleh Tabatabai, Tübingen
Participating DKTK sites: Berlin, Essen/Düsseldorf, Heidelberg, Tübingen